A dual catalyst system provides the shortest pathway for L-menthol synthesis.
نویسندگان
چکیده
We have demonstrated that a combination of enantiopure 2-diarylmethylpyrrolidines and heterogeneous Pd/BaSO(4) is an efficient catalytic system for the asymmetric hydrogenation of citral, specifically, a mixture of E-citral and Z-citral in any ratio, and that citronellal is obtained with high enantioselectivity. This dual catalyst system provides a new and more economical route to L-menthol.
منابع مشابه
Raising Distillate Selectivity and Catalyst Life Time in Fischer-Tropsch Synthesis by Using a Novel Dual-Bed Reactor
In a novel dual bed reactor Fischer-Tropsch synthesis was studied by using two diffrent cobalt catalysts. An alkali-promoted cobalt catalyst was used in the first bed of a fixed-bed reactor followed by a Rutenuim promoted cobalt catalyst in the second bed. The activity, product selectivity and accelerated deactivation of the system were assessed and compared with a conventional single bed r...
متن کاملOne-pot Synthesis of 2-amino-4H-chromene Derivatives as Potential Antimicrobial Agents using DABCO-CuCl Complex as an Effective Catalyst
A new and efficient synthesis of 2-amino-4H-chromene derivativeswhich have remarkable pharmacological properties is developed by one-pot three-component efficient reaction between aldehydes, malononitrile, and α or β-naphthol in MeOH as solvent using DABCO-CuCl complex as an effective catalyst at room temperature. The structures of synthesized compounds were characteriz...
متن کاملUltrasonic Irradiation Assisted Enantioselective Synthesis of Alzheimer’s Disease Drug Rivastigmine Tartrate by Using Nanocatalyst
A highly efficient and convenient procedure for the enantioselective synthesis of (S)-Rivastigmine tartrate, a cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer’s disease, is accomplished by the treatment of versatile, readily accessible N-Ethyl-N-methyl carbamoyl chloride with 3-hydroxyacetophenone under ultrasonic irradiation in presence of nano-K2CO3 were repo...
متن کاملAsymmetric Synthesis of New Diastereomerically Pure Spiro Oxindolopyrrolizidines and Oxindolopyrrolidines via Cycloaddition Reactions of Azomethine Ylides and Menthol-Drived Trans-Cinnamic
Chiral pyrrolidines and pyrrolizidines with spirooxindole ring systems are the central skeletons for numerous alkaloids and pharmacologically important compounds. Gelesmine, pseudotabersonine, formosanine, isoformosanine, morroniside and mitraphylline are some of the alkaloids containing spirooxindole ring systems. Derivatives of spirooxindole find very wide biological applications as anti micr...
متن کاملThe Role of Wnt Signaling Pathway on the Expression of TGFβ 1 and TGFβ 2 in Cultured Rat Cortical Astrocytes
Introduction: Astrocytes, the most abundant glia in the central nervous system, modulate neuronal survival and function. Astrocytic functions are mediated by synthesis and secretion of wide ranges of polypeptides through mechanism (s) poorly understood. Among these, TGFβs are synthesized and released by the astrocytes. In this study, the involvement of Wnt signaling pathway on the synthesi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Chemical communications
دوره 48 12 شماره
صفحات -
تاریخ انتشار 2012